A citizen petition backed by research, detransitioners, and a dozen organizations is asking the FDA to do its job. Add your comment to strengthen the case and tip the scales.
What drives me crazy is the prevailing myth that taking cross hormones just shifts your risk to the level of the opposite sex. A male taking estrogen suddenly has a lower risk of all male cancers and his risk of female cancers is just like his mom's or sister's. A female takes testosterone and all of a sudden her health risks profile matches her dad. I heard more than once "Sure the risks of stroke increases, but it just raises to the risk for cis woman". Nope, that's not how it works.
Right on. And for our son who has an inherited heart condition that his grandfather died from has just quadrupled his chances of dying early from a heart attack by taking Estrogen for 'off label' use. But, according to his doctor - it's perfectly 'safe.' It is NOT safe for any biological male - particularly him.
Why is off label use of Estrogen just fine while, for example, a doctor won't prescribe Adderall so I can lose weight & clean my house? I believe I am a very thin clean person - maybe I should lead with that.
exactly. The problem is that in the power/ prestige/ knowledge hierarchy, MD's trump clinicians. Worse yet, if you'd day, "Well your doctor is wrong." you appear a bit crazy.
I wonder if our criticisms of this ideology would be better recieved if we identified as ideology non-compliant and accused them of spaffing on our protected characteristic.
men in dresses know exactly they are intruding on women's characteristics. men deem woman to be a slur.. women afraid to be women and self iding as men do not pose a danger but are putting themselves in more danger. you can not reason with delusion, it is why the men get murdery when challenged.
Thank you. There is not nearly enough of this information out there. I have a 21 year old male client whose MD told him that taking exogenous estrogen places him in the same risk category for medical issues as a "cig-gendered" female.
Yes! And I pay a lot as a post menopausal woman for my Hormone Replacement Therapy that reduces my risk of heart disease, osteoporosis, and depression, but I don’t expect taxpayers to foot the bill.
I know of no one who has any compassion who would wish harm on a person who identifies as transgender, male or female. However, I see throughout government institutions, through DEI and free speech policies, forced affirmation; denial of biology, affirmation of identity, required language. Compelling speech is against the first amendment in the US, ie: preferred pronouns, etc. The transgender individuals see a lack of affirmation as threatening to their existence, believe non-affirmation is hate speech, violence and erasing them?
Passing as the opposite sex and forced acceptance by others or else you will feel threatened? Is this a way to
live? That you are so focused on sexuality and gender, that you must have acceptance by others?
Respect goes both ways. And people who identify as transgender need to respect those who believe in science and biology and that there are 2 sexes/genders.
Can we also have the short and long term consequences of irreversible harm to females who take testosterone?
My understanding is that the cells in the reproductive organs atrophy leading to recommendation for a hysterectomy. That the swelling of vocal cords can lead to pain. That there is male pattern baldness. Recurrent Urinary track infections among many other issues from which a female can never recover.
All this looks like TRA fuel in the form of demanding additional sympathy and disingenuous calls for far-future research: oh, so now we should trouble to feel sorry for guys whose anxiety disorder drives them to dose themselves with estrogen because it’s provably harmful to them? Miss me with that crap, they can seek treatment for their anxiety disorders instead.
Those of us who question so-called “transgender medicine” are not questioning the right to life of people who, like you, suffer from “gender dysphoria.”
What we question is that instead of helping them overcome the anxiety, depression, and feelings of distress they experience, they are encouraged to believe that medical intervention on their bodies is the solution to these problems.
And we also question the fact that thousands upon thousands of children and young people are now being led down this path, having the false beliefs implanted in them that they are transgender and that the solution lies in altering their bodies.
The fact that it worked for you should not prevent you from seeing beyond this and recognizing the harm that “gender medicine” and false transgender beliefs cause to many thousands of other people.
From the publications you present, it seems you're unaware of what's been happening around the "trans" issue over the last two decades. On the one hand, they present figures that attempt to demonstrate that the alarm is unjustified. On the other hand, they present the fallacious argument that: since Donald Trump is anti-trans, everything that questions transgender medicine and the transgender identity MUST be false.
I have nothing in common with Donald Trump. I find him repulsive, arrogant, authoritarian, narcissistic, and megalomaniacal. His assertion that there are only two sexes doesn't make that statement false simply because he shares it.
There is no "trans genocide" underway.
What exists is a growing backlash against one of the greatest absurdities in the history of medicine. That people like you interpret this backlash as a genocide is understandable: there are people—like Trump—who genuinely hate people who identify as trans; And on the other hand, it is very difficult to break with beliefs that have been held for too long.
I watched the first few minutes of the video, just to see what it was about.
Apparently, it's a complaint that the medical service isn't quickly fulfilling the wishes of transgender clients. I think the point is this: are doctors merely intermediaries between a client's desires and the means to achieve them, or are they healthcare providers?
The Cass Report was published in the UK, followed by several European countries that also published their comprehensive reviews of the evidence on puberty blockers, cross-sex hormones, and surgeries. Then the US HHS did the same, and they all reached the same conclusions: the evidence of benefit is very weak, the evidence of harm is real.
But there's more: WPATH's own evidence review team found "little or no evidence on children and adolescents." Some SOC-8 authors openly admitted to abandoning the evidence review process altogether, fearing it would “reveal little to no evidence and put us in an untenable position in terms of influencing policy or winning lawsuits.”
If access to care for people with gender dysphoria is difficult, it is partly because proponents of “transgender medicine” demonized care by equating it with conversion therapy for homosexuals.
I understand that it is difficult for people immersed in trans culture to accept that medicine is not merely a service provider but must be based first and foremost on doing no harm. And all the evidence indicates that “transgender medicine” does harm and provides few, if any, benefits.
Honey, the people pushing the "gender affirming care" are the ones trying to instigate a self-genocide. Think about it. For real. GAC increases the risk of suicide, lowers the life expectancy, reduces the dating pool, and sterilizes most survivors.
I hope that you can address the underlying and co-morbid issues you face, with love and support and find peace. But your identity that you are the opposite sex is not based in biological truth and you cannot compel other people to affirm a lie. We are happy to call you any first name that you choose, wear whatever clothing that you want, wear your hair any way that you want. Your femaleness or maleness is beautiful and should not be hated. I am sorry for any trauma that you may have experienced. But for your wholeness and wellness you must delve deeply in a safe environment into the WHY?
Or a change in trans health care? A care which is more wholistic. Not filling people’s bodies with synthetic opposite sex hormones, which are listed by the WHO as class one carcinogens, have terrible side effects, and lead to permanent sterilization (to which minors cannot consent). This is the state of GAC today. If you are over 18 at my local Planned Parenthood I could get hormones prescribed today, in my first visit, no psychological, medical or psychiatric or sexual trauma history or evaluation. No therapy for depression or anxiety?
We need to move away from the push for more pharmaceuticals to more wholistic care.
You have not acknowledged the marketing of GAC going on targeting underaged minors and the mistaken notion that if you have any gender or puberty discomfort that pharmaceuticals are the answer?
We have to address the use of pornography (of all
people no matter their identity) and autogynephilia is high is a subset of the transgender population. Should taxpayers supplement sexual fetishes?
The US Health and Human Services, after reviewing all the studies, stated in November 2025 (check the website) that trans hormones and surgeries to minors are harmful. Why is it that watchful waiting and therapy (not conversion) have more successful outcomes resolving gender dysphoria in as many as 90% of the dysphoric population ? Why do you want to continue GAC and preteen/teen hormones/blockers/possible surgeries, do you want to truly help those who can be helped by therapy and watchful waiting? Why have Norway, Sweden and the UK disassociated from WPath? Why has WPath used weak evidence in the first place? The mentioned US medical organizations are political organizations receiving donations from the profiting industries.
There are many therapies in the US which are not covered by insurance. For instance, any naturopath, functional medicine doctor, chiropractic care, any preventative supplements like probiotics, vitamins, Chlorine dioxide, DSMO and other therapies are not covered and are out of pocket for all of us. We could argue that the control of medicine by the allopathic industry, the pharmaceutical industry and insurance industries is threatening our lives as well.
Other medical procedures that I have paid out of pocket for: birth of 4 children (self employed, no maternity coverage),
Regular dentist appointments and treatments, optometrists/ glasses, orthodontic care for 2 children at $5000 each 2 decades ago, oral surgery x7 for wisdom tooth extraction and overcrowding.
Bioidentical hormones.
Homeopathic remedies, vaporizers, humidifiers for children.
On another note, when one has children to take care of, which those who are sterilizing themselves will not contend with; any after school activities, private schools, tutoring or homeschool expenses, sports, art, theater camps, music or other lessons, ordinary clothing and uniforms, all out of pocket. We are not making a fuss that we families are being eliminated because the cost of raising children is exorbitant. And those with disabled children who give even more? Are we eliminating ordinary families sacrificially taking care of their children? Yes, we had a ~ $1000 tax deduction per child/year because society has recognized the benefit of children to society.
You will find a way whether your insurance pays for what you want or think you need.
There is no doubt, that people who suffer from gender distress, dysphoria, or a wish to live as the opposite sex exist. In the past decades, from the early 1950's into the 2000's the most common treatment for adults with lifelong anxiety about their true sex was, social transition, and for some, hormones and extreme (castrating) surgeries. Although there was some public criticism of these treatments, there was also a great deal of education and acceptance of people who suffered gender identity disorders, through media talk shows like Donahue, Geraldo, etc.
Society was generally moving toward further acceptance of gender variant people until the powers-that-ought-not-to-be started focusing on transitioning children.
Nowhere in your comment do you mention protecting children. Perhaps you should read the room. Parents with Inconvenient Truth about Trans are deeply distressed about what is happening to their children. Children being groomed in schools, taken away from their parents, chemically castrated and operated on (mutilated) before they can fully understand the life-long consequences.
Thankfully some adults who have undergone transition are speaking out to protect children from what is called, in Orwellian terms, "gender-affirming care".
I am sorry if you have suffered, and happy for you if you have found joy and peace with transition. But your comment contains a great deal of trans agenda rhetoric and group-think, and you mistakenly place the blame on Trump.
The current public focus on the realities of gender transitions has emerged due to the sexual grooming and mutilation of children.
It is no surprise that children who are told they will commit suicide if they don't get a "life-saving treatment" may do just that. Adults need to take responsibility to protect children, not subject them to trans cult ideology. Thanks for revealing yourself. At first, you painted a picture of yourself as a victim, suffering from persecution. As soon as children were mentioned the gloves came off, and you showed your true colors. Keep going, let's see more about what you are really about.
I don’t understand how this study is anti-trans. Maybe I am not reading all of it ? I personally want as much information as possible about drugs I take so I am prepared. The FDA owes it to the public to more research. Family members who tell me they are glad they have transitioned also tell me that they were suicidal the first year on estrogen. They said estrogen gave them more intense feelings than they had with their biological testosterone. This is like second puberty in a body unprepared for these hormones. We need to know how it impacts people.
What drives me crazy is the prevailing myth that taking cross hormones just shifts your risk to the level of the opposite sex. A male taking estrogen suddenly has a lower risk of all male cancers and his risk of female cancers is just like his mom's or sister's. A female takes testosterone and all of a sudden her health risks profile matches her dad. I heard more than once "Sure the risks of stroke increases, but it just raises to the risk for cis woman". Nope, that's not how it works.
Right on. And for our son who has an inherited heart condition that his grandfather died from has just quadrupled his chances of dying early from a heart attack by taking Estrogen for 'off label' use. But, according to his doctor - it's perfectly 'safe.' It is NOT safe for any biological male - particularly him.
Why is off label use of Estrogen just fine while, for example, a doctor won't prescribe Adderall so I can lose weight & clean my house? I believe I am a very thin clean person - maybe I should lead with that.
exactly. The problem is that in the power/ prestige/ knowledge hierarchy, MD's trump clinicians. Worse yet, if you'd day, "Well your doctor is wrong." you appear a bit crazy.
i just want the crimes against humanity charges filed against the medical industry....
I wonder if our criticisms of this ideology would be better recieved if we identified as ideology non-compliant and accused them of spaffing on our protected characteristic.
men in dresses know exactly they are intruding on women's characteristics. men deem woman to be a slur.. women afraid to be women and self iding as men do not pose a danger but are putting themselves in more danger. you can not reason with delusion, it is why the men get murdery when challenged.
Thank you. There is not nearly enough of this information out there. I have a 21 year old male client whose MD told him that taking exogenous estrogen places him in the same risk category for medical issues as a "cig-gendered" female.
Well that was a wild guess.
Done. Brilliant work. Thank you.
There are many arguments against transgenderism.
I agree with those, but want to add one more:
How much is all this "transgender care" costing ordinary people?
Why should ordinary people be required to pay for the fantasies of these people?
I am being penalized, through my Medicare premiums, by these people's demands.
Yes! And I pay a lot as a post menopausal woman for my Hormone Replacement Therapy that reduces my risk of heart disease, osteoporosis, and depression, but I don’t expect taxpayers to foot the bill.
I know of no one who has any compassion who would wish harm on a person who identifies as transgender, male or female. However, I see throughout government institutions, through DEI and free speech policies, forced affirmation; denial of biology, affirmation of identity, required language. Compelling speech is against the first amendment in the US, ie: preferred pronouns, etc. The transgender individuals see a lack of affirmation as threatening to their existence, believe non-affirmation is hate speech, violence and erasing them?
Passing as the opposite sex and forced acceptance by others or else you will feel threatened? Is this a way to
live? That you are so focused on sexuality and gender, that you must have acceptance by others?
Respect goes both ways. And people who identify as transgender need to respect those who believe in science and biology and that there are 2 sexes/genders.
Can we also have the short and long term consequences of irreversible harm to females who take testosterone?
My understanding is that the cells in the reproductive organs atrophy leading to recommendation for a hysterectomy. That the swelling of vocal cords can lead to pain. That there is male pattern baldness. Recurrent Urinary track infections among many other issues from which a female can never recover.
Thanks. Did. I referred to my best friend's (ti) kid, not having a kid of my own.
Signed, and mostly handwritten. Thank you.
All this looks like TRA fuel in the form of demanding additional sympathy and disingenuous calls for far-future research: oh, so now we should trouble to feel sorry for guys whose anxiety disorder drives them to dose themselves with estrogen because it’s provably harmful to them? Miss me with that crap, they can seek treatment for their anxiety disorders instead.
Those of us who question so-called “transgender medicine” are not questioning the right to life of people who, like you, suffer from “gender dysphoria.”
What we question is that instead of helping them overcome the anxiety, depression, and feelings of distress they experience, they are encouraged to believe that medical intervention on their bodies is the solution to these problems.
And we also question the fact that thousands upon thousands of children and young people are now being led down this path, having the false beliefs implanted in them that they are transgender and that the solution lies in altering their bodies.
The fact that it worked for you should not prevent you from seeing beyond this and recognizing the harm that “gender medicine” and false transgender beliefs cause to many thousands of other people.
From the publications you present, it seems you're unaware of what's been happening around the "trans" issue over the last two decades. On the one hand, they present figures that attempt to demonstrate that the alarm is unjustified. On the other hand, they present the fallacious argument that: since Donald Trump is anti-trans, everything that questions transgender medicine and the transgender identity MUST be false.
I have nothing in common with Donald Trump. I find him repulsive, arrogant, authoritarian, narcissistic, and megalomaniacal. His assertion that there are only two sexes doesn't make that statement false simply because he shares it.
There is no "trans genocide" underway.
What exists is a growing backlash against one of the greatest absurdities in the history of medicine. That people like you interpret this backlash as a genocide is understandable: there are people—like Trump—who genuinely hate people who identify as trans; And on the other hand, it is very difficult to break with beliefs that have been held for too long.
I watched the first few minutes of the video, just to see what it was about.
Apparently, it's a complaint that the medical service isn't quickly fulfilling the wishes of transgender clients. I think the point is this: are doctors merely intermediaries between a client's desires and the means to achieve them, or are they healthcare providers?
The Cass Report was published in the UK, followed by several European countries that also published their comprehensive reviews of the evidence on puberty blockers, cross-sex hormones, and surgeries. Then the US HHS did the same, and they all reached the same conclusions: the evidence of benefit is very weak, the evidence of harm is real.
But there's more: WPATH's own evidence review team found "little or no evidence on children and adolescents." Some SOC-8 authors openly admitted to abandoning the evidence review process altogether, fearing it would “reveal little to no evidence and put us in an untenable position in terms of influencing policy or winning lawsuits.”
If access to care for people with gender dysphoria is difficult, it is partly because proponents of “transgender medicine” demonized care by equating it with conversion therapy for homosexuals.
I understand that it is difficult for people immersed in trans culture to accept that medicine is not merely a service provider but must be based first and foremost on doing no harm. And all the evidence indicates that “transgender medicine” does harm and provides few, if any, benefits.
Honey, the people pushing the "gender affirming care" are the ones trying to instigate a self-genocide. Think about it. For real. GAC increases the risk of suicide, lowers the life expectancy, reduces the dating pool, and sterilizes most survivors.
I hope that you can address the underlying and co-morbid issues you face, with love and support and find peace. But your identity that you are the opposite sex is not based in biological truth and you cannot compel other people to affirm a lie. We are happy to call you any first name that you choose, wear whatever clothing that you want, wear your hair any way that you want. Your femaleness or maleness is beautiful and should not be hated. I am sorry for any trauma that you may have experienced. But for your wholeness and wellness you must delve deeply in a safe environment into the WHY?
Or a change in trans health care? A care which is more wholistic. Not filling people’s bodies with synthetic opposite sex hormones, which are listed by the WHO as class one carcinogens, have terrible side effects, and lead to permanent sterilization (to which minors cannot consent). This is the state of GAC today. If you are over 18 at my local Planned Parenthood I could get hormones prescribed today, in my first visit, no psychological, medical or psychiatric or sexual trauma history or evaluation. No therapy for depression or anxiety?
We need to move away from the push for more pharmaceuticals to more wholistic care.
You have not acknowledged the marketing of GAC going on targeting underaged minors and the mistaken notion that if you have any gender or puberty discomfort that pharmaceuticals are the answer?
We have to address the use of pornography (of all
people no matter their identity) and autogynephilia is high is a subset of the transgender population. Should taxpayers supplement sexual fetishes?
The US Health and Human Services, after reviewing all the studies, stated in November 2025 (check the website) that trans hormones and surgeries to minors are harmful. Why is it that watchful waiting and therapy (not conversion) have more successful outcomes resolving gender dysphoria in as many as 90% of the dysphoric population ? Why do you want to continue GAC and preteen/teen hormones/blockers/possible surgeries, do you want to truly help those who can be helped by therapy and watchful waiting? Why have Norway, Sweden and the UK disassociated from WPath? Why has WPath used weak evidence in the first place? The mentioned US medical organizations are political organizations receiving donations from the profiting industries.
One only needs to watch the first minute of Abigail Thorn's video to see the violence. Thanks for the link.
There are many therapies in the US which are not covered by insurance. For instance, any naturopath, functional medicine doctor, chiropractic care, any preventative supplements like probiotics, vitamins, Chlorine dioxide, DSMO and other therapies are not covered and are out of pocket for all of us. We could argue that the control of medicine by the allopathic industry, the pharmaceutical industry and insurance industries is threatening our lives as well.
Other medical procedures that I have paid out of pocket for: birth of 4 children (self employed, no maternity coverage),
Regular dentist appointments and treatments, optometrists/ glasses, orthodontic care for 2 children at $5000 each 2 decades ago, oral surgery x7 for wisdom tooth extraction and overcrowding.
Bioidentical hormones.
Homeopathic remedies, vaporizers, humidifiers for children.
On another note, when one has children to take care of, which those who are sterilizing themselves will not contend with; any after school activities, private schools, tutoring or homeschool expenses, sports, art, theater camps, music or other lessons, ordinary clothing and uniforms, all out of pocket. We are not making a fuss that we families are being eliminated because the cost of raising children is exorbitant. And those with disabled children who give even more? Are we eliminating ordinary families sacrificially taking care of their children? Yes, we had a ~ $1000 tax deduction per child/year because society has recognized the benefit of children to society.
You will find a way whether your insurance pays for what you want or think you need.
If a total ban on coverage of trans surgeries is the result of going after children, then so be it. You only have yourself to blame.
There is no doubt, that people who suffer from gender distress, dysphoria, or a wish to live as the opposite sex exist. In the past decades, from the early 1950's into the 2000's the most common treatment for adults with lifelong anxiety about their true sex was, social transition, and for some, hormones and extreme (castrating) surgeries. Although there was some public criticism of these treatments, there was also a great deal of education and acceptance of people who suffered gender identity disorders, through media talk shows like Donahue, Geraldo, etc.
Society was generally moving toward further acceptance of gender variant people until the powers-that-ought-not-to-be started focusing on transitioning children.
Nowhere in your comment do you mention protecting children. Perhaps you should read the room. Parents with Inconvenient Truth about Trans are deeply distressed about what is happening to their children. Children being groomed in schools, taken away from their parents, chemically castrated and operated on (mutilated) before they can fully understand the life-long consequences.
Thankfully some adults who have undergone transition are speaking out to protect children from what is called, in Orwellian terms, "gender-affirming care".
I am sorry if you have suffered, and happy for you if you have found joy and peace with transition. But your comment contains a great deal of trans agenda rhetoric and group-think, and you mistakenly place the blame on Trump.
The current public focus on the realities of gender transitions has emerged due to the sexual grooming and mutilation of children.
You are confusing protecting children with "anti-transgender." The links you provide are woke propaganda and nonsense.
It is no surprise that children who are told they will commit suicide if they don't get a "life-saving treatment" may do just that. Adults need to take responsibility to protect children, not subject them to trans cult ideology. Thanks for revealing yourself. At first, you painted a picture of yourself as a victim, suffering from persecution. As soon as children were mentioned the gloves came off, and you showed your true colors. Keep going, let's see more about what you are really about.
I don’t understand how this study is anti-trans. Maybe I am not reading all of it ? I personally want as much information as possible about drugs I take so I am prepared. The FDA owes it to the public to more research. Family members who tell me they are glad they have transitioned also tell me that they were suicidal the first year on estrogen. They said estrogen gave them more intense feelings than they had with their biological testosterone. This is like second puberty in a body unprepared for these hormones. We need to know how it impacts people.